• Users Online: 140
  • Print this page
  • Email this page
Year : 2022  |  Volume : 8  |  Issue : 3  |  Page : 83-88

Cardiac comorbidities impact on the outcomes in severe COVID-19 infection

1 Department of Cardiology, AL-Azhar University, Cairo, Egypt
2 Department of Radiodiagnosis, AL-Azhar University, Cairo, Egypt
3 Department of Clinical Pathology, Faculty of Medicine for Girls, AL-Azhar University, Cairo, Egypt
4 Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Correspondence Address:
Prof. Mohamed Zahran
Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijca.ijca_10_22

Rights and Permissions

Background: COVID-19 is now a global pandemic, with the officially recorded number of affected individuals approaching 4 billion patients. Aim of the Work: Our purpose is to study the effect of cardiac comorbidities on the outcomes of severely infected COVID-19 patients. Patients and Methods: This study included 147 patients with severe COVID-19. All data were analyzed regarding demographic risk factors, associated diseases, mode of oxygen therapy administration, and echocardiography. Results: The death rate (DR) in patients with severe COVID-19 and no comorbidities was 7.7%. In patients who had only one risk factor as smoking, hypertension (HTN), or diabetes mellitus (DM), the DR was 16.7%, 33.3%, and 8.3%, respectively. The addition of one risk factor to HTN increased DR in the case of DM (36.8%) and in the case of smoking (40%). Regarding the outcomes, the percentage of the patients affected was as follows: impaired left ventricular ejection fraction (LVEF) <50% (19.7%), dilated right ventricular (RV) basal dimension (12.2%), decreased tricuspid annular plane systolic excursion <17 mm (8.2%), increased SPAP >30 mmHg (53.7%), and pericardial effusion (23.1%). Patients were subclassified according to the presence of HTN. The hypertensive group had increased LV wall thickness and LV end-systolic dimension and impaired LVEF and fraction of shortening than normotensive patients. DR for females and males treated by high-flow nasal cannula was (3.3% vs. 6.9%), continuous positive airway pressure (0% vs. 3.2%), and mechanical ventilation (100% vs. 90.5%). The suggested score was significantly higher in the death group (P < 00001). The DR increased markedly with the incremental rising score. Conclusions: Comorbidities, age, and delayed presentation with decreased oxygen saturation had a cumulative risk that can predict the outcome of COVID-19 patients. The presence of HTN alone or associated with other risk factors had a higher DR than other risk factors.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded55    
    Comments [Add]    

Recommend this journal